![]() ![]() Lower plasma levels of PC have been observed in individuals with Alzheimer's disease and other types of dementia, while the protective colonic mucus PC content has been shown to be reduced by 70% in individuals with ulcerative colitis. Choline provided by PC is a precursor for the synthesis of acetylcholine, an important neurotransmitter centrally in the brain, and necessary peripherally for muscle control and other aspects of cholinergic signalling. This includes fat and cholesterol metabolism, homocysteine metabolism, fetal development, neurocognitive health and development, and liver detoxification of chemicals, heavy metals, and xenobiotics. Sufficient levels of PC are necessary for many biochemical pathways, supporting critical functions and physiology. ![]() Supplemental intake of PC is one means of providing sufficient choline for the body's needs. The risk of choline deficiency is higher in men, postmenopausal women, vegans or vegetarians, and individuals with genetic polymorphisms related to folate or choline metabolism. Although small amounts of choline can be synthesized from methionine or serine, it is considered an essential nutrient and must be obtained from the diet.Īlthough thresholds have been established for adequate intake of choline, studies have shown that this may not be suffiicient for prevention of symptoms of choline deficiency such as fatty liver or muscle damage. PC is a normal constituent of bile and facilitates fat emulsification, absorption, and transport. It is a vital component required for cellular and intracellular membrane integrity, structure, and function. Phosphatidyl Choline (PC) is the most predominant phospholipid building block of animal-and plant-cell membranes, and an integral part of the structure of curculating lipoproteins. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |